Alpha Blocker Treatment and Intra-operative Floppy Iris Syndrome

Alpha antagonists and intraoperative floppy iris syndrome: A spectrum

BACKGROUND To determine occurrence of features of intraoperative floppy iris syndrome (IFIS) during cataract surgery in patients taking systemic alpha-antagonists (AA). METHODS We prospectively studied patients on AA and who underwent phacoemulsification. The following were recorded: pupil diameter preoperatively, iris flaccidity, iris prolapse and peroperative miosis. RESULTS We studied 40...

Intraoperative floppy-iris syndrome.

OBJECTIVE Intraoperative-floppy iris syndrome (IFIS) has been recently described. It has been demonstrated that this new syndrome complicates cataract surgery. In this paper we have reviewed the syndrome, and offer practical information specially related to the origin and management of this syndrome and we offer practical information. MATERIAL AND METHODS A review of the related medical liter...

The Intraoperative Floppy Iris Syndrome

A t the annual meeting of the ASCRS in April, John R. Campbell, MD, and I reported on two companion studies that we conducted to examine the incidence, characteristics, surgical outcomes, and etiology of floppy irides during cataract surgery.1,2 We named this condition the intraoperative floppy iris syndrome (IFIS) (Figures 1 to 3). Based upon retrospective observations by Dr. Campbell regardin...

Intraoperative floppy iris syndrome: pathophysiology, prevention, and treatment.

PURPOSE To extend upon previous reports, observations, and discussions of intraoperative floppy iris syndrome (IFIS) with the goal of providing new insight into the syndrome's pathophysiology, prevention, and treatment. METHODS Following a review of IFIS and its relationship to autonomic pharmacology, evidence for anatomic changes following exposure of humans and other animals to autonomic dr...

Silodosin-associated intraoperative floppy iris syndrome